Metronidazole therapy for periodontitis

Abstract

Considerable data have accumulated which suggest that some or most forms of periodontal disease are specific, albeit chronic, bacteriological infections (1, 2). In most instances the plaque flora re-moved from infiamed sites are dominat-ed by anaerobic organisms such as spi-rochetes, bacteroides and eubacterium species (1^). In some instances, the microaerophilic organism Actinobacil-lus actinomycetemcomitans (Aa) has been associated with periodontal path-ology (5, 6). These findings indicate that treatments aimed at controlling peri-odontal disease could contain an anti-