Concepedia

99mTc-labeled monomeric and dimeric NGR peptides for SPECT imaging of CD13 receptor in tumor-bearing mice

Wenhui Ma, Fei Kang, Zhe Wang, Weidong Yang, Guiyu Li, Xiaowei Ma, Guoquan Li, Kai Chen, Yingqi Zhang, Jing Wang

Amino Acids · 2013 · 36 citations · 28 references

DOI

Concepts

References

28

Cancer Treatment by Targeted Drug Delivery to Tumor Vasculature in a Mouse Model

Wadih Arap, Renata Pasqualini, Erkki Ruoslahti · Science · 1998 · 2.1K citations

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Aminopeptidase N is a receptor for tumor-homing peptides and a target for inhibiting angiogenesis.

Renata Pasqualini, Erkki Koivunen, Renate Kain et al. · PubMed · 2000 · 867 citations

, , +16

CD13/APN is activated by angiogenic signals and is essential for capillary tube formation

Shripad V. Bhagwat, Johanna Lahdenranta, Ricardo J. Giordano et al. · Blood · 2001 · 346 citations · Full text

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microPET imaging of glioma integrin {alpha}v{beta}3 expression using (64)Cu-labeled tetrameric RGD peptide.

Yun Wu, Xianzhong Zhang, Zhengming Xiong et al. · PubMed · 2005 · 329 citations

, , +17

Differential binding of drugs containing the NGR motif to CD13 isoforms in tumor vessels, epithelia, and myeloid cells.

Flavio Curnis, Gianluigi Arrigoni, Angelina Sacchi et al. · PubMed · 2002 · 279 citations

, , +14