A perfused tail artery preparation from the rat

Abstract

Abstract The isolated perfused tail artery of the rat responds by constriction to 1·0 ng (-)-noradrenaline, and would be suitable for the assay of sympathomimetic amines. Electrical stimulation of this preparation is shown to activate solely postganglionic adrenergic nerve terminals. Tachyphyllaxis to angiotensin, vasopressin and bradykinin preclude the use of this preparation for their assay.