Tooth sizes in two males with deletions of the long arm of the Y‐chromosome

Abstract

Permanent and deciduous tooth crown sizes in two males with deletions of the long arm of the Y chromosome and their first-degree relatives were examined. The first proband with a deletion in the proximal part of Yq11 showed definitely smaller teeth than his father or population control males. The second proband with a deletion in the distal part of Yq11 showed large or normal sized teeth compared to his brother or population control males. These data support the results of earlier studies indicating a promoting effect of the Y chromosome on tooth growth, and suggest that the location of the growth-promoting gene(s) is in Yq11. It is postulated that statural growth is affected by the same gene(s).