Concepedia

Both PI3K/Akt and ERK1/2 pathways participate in the protection by dexmedetomidine against transient focal cerebral ischemia/reperfusion injury in rats

Yong-Man Zhu, Can-Can Wang, Long Chen, Ling-Bo Qian, Leilei Ma, Jing Yu, Manhua Zhu, Chuanyun Wen, Lina Yu, Min Yan

Brain Research · 2012 · 174 citations · 27 references

DOI

Concepts

References

27

Reversible middle cerebral artery occlusion without craniectomy in rats.

Enrique Zea Longa, Philip R. Weinstein, Shaun W. Carlson et al. · Stroke · 1989 · 7.5K citations · Full text

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MEK1 protein kinase inhibition protects against damage resulting from focal cerebral ischemia

Alessandro Alessandrini, Shobu Namura, Michael A. Moskowitz et al. · Proceedings of the National Academy of Sciences · 1999 · 465 citations

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Dexmedetomidine Improves Neurologic Outcome from Incomplete Ischemia in the Rat Reversal by the α2-Adrenergic Antagonist Atipamezole

William E. Hoffman, E. Kochs, Christian Werner et al. · Anesthesiology · 1991 · 284 citations · Full text

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Hypothalamic PI3K and MAPK differentially mediate regional sympathetic activation to insulin

Kamal Rahmouni, Donald A. Morgan, Gina Morgan et al. · Journal of Clinical Investigation · 2004 · 182 citations · Full text

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Ischemic postconditioning protects brain from ischemia/reperfusion injury by attenuating endoplasmic reticulum stress-induced apoptosis through PI3K-Akt pathway

Yajing Yuan, Qulian Guo, Zhi Ye et al. · Brain Research · 2010 · 146 citations

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