Antibacterial Property of Tetramethyl-Pyrazine from the Stem of Jatropha podagrica

Abstract

The methanolic extract of stem of Jatropha podagrica Hook has demonstrated antibacterial activity against only gram positive microorganisms. Fractionation of this extract resulted in a number of active fractions. One of them contained the amide alkaloid tetramethylpyrazine. The presence of this alkaloid has previously not been reported in any Jatropha species. The structures of [the] other active compounds are still being determined. Key Word Index Jatropha podagrica - Euphorbiaceae - Amide Alkaloid - Tetramethylpyrazine - Antibacterial Property.