Cytotoxic Constituents of Muntingia calabura Leaves and Stems Collected in Thailand

Abstract

From samples of Muntingia calabura leaves and stems of Thai origin were obtained the cytotoxic flavonoids chrysin, 2′, 4′-dihydroxychalcone, and galangin 3, 7-dimethyl ether. These compounds were active against one or more of a panel of human and murine cell lines. Also isolated were the inactive compounds, 5, 7-dihydroxy-8-methoxyflavonol, tiliroside and buddlenoid A.