1,6-Electrocyclization Reactions of Acceptor-substituted 2,3-Divinylindoles to Functionalized Carbazoles

Abstract

The syntheses and thermal 1,6-electrocyclization reactions of acceptor-substituted 2.3-divinylindales, which give rise to functionalized carbazole derivatives, are described.Functionalized and/or annellated carbazoles and carbazole alkaloids have now attained considerable interest as pharmacologically active lead substances as well as being, for example, compounds with antibiotic and anti-tumour Hence.there is a still a major requirement for short and highly selective syntheses of these classes of heterocyclic compounds starting from readily available substrates.In continuation of our work on convergent pericyclic methods for the