WW domain-containing oxidoreductase is involved in upregulation of matrix metalloproteinase 9 by Epstein–Barr virus latent membrane protein 2A

WWOX, a novel WW domain-containing protein mapping to human chromosome 16q23.3-24.1, a region frequently affected in breast cancer.

Andrzej K. Bednarek, K J Laflin, Rachael Daniel et al. · PubMed · 2000 · 428 citations

Life Sciences, Genetics, Molecular Genetics +10

Epstein-Barr Virus LMP2A Transforms Epithelial Cells, Inhibits Cell Differentiation, and Activates Akt

Frank Scholle, Katharine M. Bendt, Nancy Raab‐Traub · Journal of Virology · 2000 · 275 citations

Medicine, Cell Biology, Oncology +17

Epstein-Barr Virus-Encoded LMP2A Induces an Epithelial–Mesenchymal Transition and Increases the Number of Side Population Stem-like Cancer Cells in Nasopharyngeal Carcinoma

Qing‐Li Kong, Li-Juan Hu, Jing-Yan Cao et al. · PLoS Pathogens · 2010 · 193 citations · Full text

Medicine, Cell Biology, Oncology +17

Latent Membrane Protein 2A of Epstein-Barr Virus Binds WW Domain E3 Protein-Ubiquitin Ligases That Ubiquitinate B-Cell Tyrosine Kinases

Gösta Winberg, Liudmila Matskova, Fu Chen et al. · Molecular and Cellular Biology · 2000 · 170 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +17

Physical and Functional Interactions between the Wwox Tumor Suppressor Protein and the AP-2γ Transcription Factor

Rami I. Aqeilan, Alexey Palamarchuk, Ronald J. Weigel et al. · Cancer Research · 2004 · 161 citations · Full text

Life Sciences, Molecular Biology, Oncology +13