Intestinal surgical resection disrupts electrical rhythmicity, neural responses, and interstitial cell networks

W/kit gene required for interstitial cells of Cajal and for intestinal pacemaker activity

Jan D. Hulzinga, Lars Thuneberg, Michael Klüppel et al. · Nature · 1995 · 1.4K citations

Life Sciences, Genetics, Molecular Biology +10

Mutation of the proto‐oncogene c‐kit blocks development of interstitial cells and electrical rhythmicity in murine intestine.

Sean M. Ward, Alan J. Burns, Shigeko Torihashi et al. · The Journal of Physiology · 1994 · 815 citations

Life Sciences, Developmental Biology, Genetics +14

Surgical Manipulation of the Gut Elicits an Intestinal Muscularis Inflammatory Response Resulting in Postsurgical Ileus

Jörg C. Kalff, Wolfgang H. Schraut, Richard L. Simmons et al. · Annals of Surgery · 1998 · 537 citations

Medicine, Immunology, Surgery +17

c-kit-Dependent development of interstitial cells and electrical activity in the murine gastrointestinal tract

Shigeko Torihashi, Sean M. Ward, Shin‐Ichi Nishikawa et al. · Cell and Tissue Research · 1995 · 399 citations

Life Sciences, Cell Biology, Developmental Biology +17

Blockade of kit signaling induces transdifferentiation of interstitial cells of Cajal to a smooth muscle phenotype

Shigeko Torihashi, Katsuhide Nishi, Yoshiko Tokutomi et al. · Gastroenterology · 1999 · 298 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +12