Chemical Communications · 2004 · 256 citations · 20 references
PharmacyBiotechnologyPharmaceuticsDrug DeliveryMolecular ImagingNanomaterialsCancer NanomedicineNanomedicineNanoparticle CharacterizationNanoparticle DesignNanoparticle FormulationsNanoparticle SynthesisCell-penetrating Peptide NanocarriersLung AdenocarcinomaMicroemulsion SynthesisNanoparticle ConjugationNanoparticle Imaging AgentsNanoparticle-based ProbesNanoparticlesSilica-based Nanoparticles
Water-in-oil (w/o) microemulsion synthesis of 70 nm size monodisperse TAT (a cell penetrating peptide, CPP) conjugated, FITC (fluorescein isothiocyanate) doped silica nanoparticles (TAT-FSNPs) is reported; human lung adenocarcinoma (A549) cells (in vitro) and rat brain tissue (in vivo) were successfully labeled using TAT-FSNPs.
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