CORTISONE ACETATE IN SKIN DISEASE

Abstract

CORTISONE acetate (cortone®) has been found to have a local effect in various diseases of the eye, especially those of an inflammatory or exudative nature.1In ophthalmology, suspensions of cortisone have been used locally as drops and by subconjunctival injection and ointment. In some instances it was necessary to dilute the suspension 1:4 because of local irritation. Special ophthalmic preparations of cortisone with buffered solutions are available. However, topical application does not have any effect on exudation in the vitreous body according to Woods.2After injection into the anterior chamber Woods1hhas reported a heavy flocculent mass disappearing within 24 to 48 hours. After subconjunctival injection remnants can be seen for several weeks. The advantages of local cortisone therapy are obvious. These include the utilization of smaller quantities of medication, avoidance of systemic side-effects, therapy of ambulatory patients, and therapy of aged or debilitated patients. In one