Acquired Toxoplasmosis

Abstract

THE first published cases of acquired toxoplasmosis in man were reported in 19401 and 1941.2 , 3 Since then approximately 55 additional cases have appeared in the medical literature in English. In many of these the parasite was not isolated or was found only after the death of the patient. Of 14 cases of acquired toxoplasmosis ending fatally1 2 3 4 5 6 7 8 9 10 11 12 the organism was recovered by animal inoculation in only 4.2 , 3 , 11 , 12 Since the diagnosis is often made late in the disease, few patients have been studied extensively, and little is known of the efficacy of treatment. Recently, pyrimethamine (2:4′-diamino-5-[4′-chlorphenyl]-6-ethyl pyrimidine)¶ and triple sulfonamides have been . . .