Mosaicism in a Mother with a Mongol Child

Abstract

Furthermore, had the extent of the epidemic been more fully appreciated it might have been possible to co-ordinate the work of the various practitioners in the district and to have advised upon the use of such protective measures as gamma-globulin.Summary Details of an epidemic of infectious hepatitis occurring in a village community are reported.The source of infection appeared to be the village primary school, where at least one food-handler was affected and toilet facilities were not regarded as ideal.The epidemic was subsequently characterized by a high incidence of spread to family contacts of the children originally affected.Although the clinical course was mild in children, a young married woman developed acute hepatic necrosis and died.It is believed that the extent of the epidemic was far greater than the 61 cases reported would indicate, and it is suggested that some form of notification of infectious hepatitis is desirable in order to improve our knowledge of the aetiology and epidemiology of this disease.We wish to record our thanks to Drs.P. C. Green, R. H. Kipping, W. J. Low, and H. N.