Whole Exome Sequencing Identifies a Causal <i>RBM20</i> Mutation in a Large Pedigree With Familial Dilated Cardiomyopathy

Abstract

Whole exome sequencing of remotely related dilated cardiomyopathy subjects from a large, multiplex family, followed by systematic filtering, identified a causal RBM20 mutation without the need for linkage analysis.