FREE RADICAL SCAVENGERS, CATALASE AND SUPEROXIDE DISMUTASE PROVIDE PROTECTION FROM OXALATE-ASSOCIATED INJURY TO LLC-PK ₁ AND MDCK CELLS

Abstract

Results of the present study indicate that both Ox and COM crystals are injurious to renal epithelial cells and the injury is associated with generation of free radicals. Cells of proximal tubular origin are more susceptible than those of distal tubules and collecting ducts. Free radical scavengers, catalase and SOD provide significant protection.