Laser technologies for fabricating individual implants and matrices for tissue engineering

A. V. Evseev, V. Ya. Panchenko, J. J. A. Barry, Martin J. Whitaker, Steven M. Howdle

Journal of Optical Technology · 2007 · 17 citations · 0 references

Concepts

Abstract

This paper presents the results of work on the development and modification of laser methods of rapid prototyping and fabrication of individual implants and matrices for tissue engineering. A technology has been developed for shaping mineral-polymer bioactive structures, based on laser photopolymerization of a liquid mixture of polyfunctional acrylic oligomers with microparticles of hydroxyapatite. A method is proposed and developed for surface-selective laser sintering, making it possible to sinter polymeric microparticles without melting them completely, but only submelting their surface. This made it possible to obtain bioactive polymeric matrices based on bioresorbable aliphatic polyesters.