Archives of Neurology · 2005 · 74 citations · 11 references
It appears unlikely that the PD clinical research community will perceive future neurosurgical interventions for PD, such as gene-transfer therapies, as truly efficacious unless a sham-control condition is used to test it.
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Transplantation of Embryonic Dopamine Neurons for Severe Parkinson's Disease
Curt R. Freed, Paul Greene, Robert E. Breeze et al. · New England Journal of Medicine · 2001 · 2.3K citations · Full text
Randomized, double-blind trial of glial cell line-derived neurotrophic factor (GDNF) in PD
John G. Nutt, Kim J. Burchiel, Cynthia Comella et al. · Neurology · 2003 · 817 citations