LSD: No Teratogenic Action in Rats, Mice, and Hamsters

Abstract

Lysergic acid diethylamide tartrate was given to 98 pregnant rats, 67 mice, and 22 hamsters as a single dose of 5 to 500 micrograms per kilogram of body weight per day either at the beginning of gestation or during the period of organogenesis. Examination of the 1003 rat fetuses, 521 mouse fetuses, and 189 hamster fetuses obtained failed to prove any abortifacient, teratogenic, or growth-depressing effects.