The Protective Effect of Hyperbaric Oxygenation in Experimental Cerebral Edema

Abstract

pREVIOUS communications indicate that hyperbaric oxygenation (HPO) may be beneficial in the management of ischemic disorders of the brain, l~176 Other investigators~,~, have described the effects of high pressure oxygen on cerebral trauma. The cerebral vasoconstriction caused by hyperbaric oxygenationla,z~,~6,-~ '-'G in combination with the increased available oxygen ~,~s,2~ are factors that might be of value in the treatment of cerebral edema. The present study was undertaken to evaluate the effect of hyperbaric oxygenation on cerebral edema produced by a slowly expanding intracranial space-occupying lesion. Method