Clinical significance of B7-H4 expression in matched non-small cell lung cancer brain metastases and primary tumors

Abstract

NSCLC patients with high B7-H4 expression may benefit from aggressive treatment and close surveillance. Furthermore, our study suggests that B7-H4 may play an important role in the metastatic process of NSCLC and is promising to be a new immune checkpoint molecule for future antitumoral immunotherapy.