Publication | Open Access
Simple Protocol for NMR Analysis of the Enantiomeric Purity of Primary Amines
107
Citations
2
References
2006
Year
EngineeringSimple ProtocolChiral Primary AminesEnantiomeric PurityOrganic ChemistryDrug PurityAnalytical ChemistryStereoselective SynthesisPrimary AminesRemote StereocentersBiochemistrySolution Nmr SpectroscopyPharmacologyAsymmetric CatalysisEnantioselective SynthesisBiomolecular EngineeringMedicineDerivative (Chemistry)Drug Analysis
[reaction: see text] A practically simple three-component chiral derivatizing protocol for determining the enantiopurity of 13 chiral primary amines by (1)H NMR spectroscopic analysis is described, including analysis of those that contain remote stereocenters.
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