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High-performance liquid chromatographic method for the simultaneous determination of the camptothecin derivative irinotecan hydrochloride, CPT-11, and its metabolites SN-38 and SN-38 glucuronide in rat plasma with a fully automated on-line solid-phase extraction system, PROSPEKT

BiochemistryBioassay-guided IsolationMedicineGas ChromatographyBioanalysisAnalytical ChemistryRat PlasmaLiquid ChromatographyClinical ChemistryChromatographic AnalysisPharmacologySn-38 GlucuronidePharmacokineticsMetabolites Sn-38ChromatographyDrug Analysis