Comparison of Intramuscular Olanzapine, Orally Disintegrating Olanzapine Tablets, Oral Risperidone Solution, and Intramuscular Haloperidol in the Management of Acute Agitation in an Acute Care Psychiatric Ward in Taiwan

Abstract

These findings suggest that intramuscular olanzapine, orally disintegrating olanzapine tablets, and oral risperidone solution are as effective treatments as intramuscular haloperidol for patients with acute agitation. Intramuscular olanzapine and disintegrating olanzapine tablets are more effective than intramuscular haloperidol in the early phase of the intervention. There is no significant difference in effectiveness among intramuscular olanzapine, orally disintegrating olanzapine tablets, and oral risperidone solution.