Mutation screening and association study of the candidate prostate cancer susceptibility genesMSR1,PTEN, andKLF6

Abstract

We found no evidence that MSR1 and PTEN germline mutations are associated with prostate cancer risk in Jews. The negative association between KLF6 IVS1-27A and prostate cancer risk supports a population-specific effect of susceptibility alleles in prostate tumorigenesis.