Solubilized Receptor for Vitamin B₁₂—Intrinsic Factor Complex from Human Intestine

Abstract

S ummary . A specific receptor for intrinsic factor‐vitamin B 12 complex has been prepared in soluble form from human intestinal mucosal cell membranes employing Triton X‐100. The extraction procedure has not detectably altered its characteristics relative to membrane‐bound receptor. It appears to be macromolecule containing critical peptide and disulphide bonds.