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Statistical Analysis of Modes of Inheritance for Pesticide Resistance
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1990
Year
FitnessBioassay DataGeneticsToxicology TestingLaboratory Animal StudyToxicologyBiostatisticsInsecticidePublic HealthStatisticsStandard X2 StatisticStatistical GeneticsPest ManagementGenetic VariationExperimental ToxicologyPopulation GeneticsPesticide ResistanceCrop ProtectionModified X2 StatisticInduced ResistanceMedicine
Use of the standard x2 statistic for testing modes of inheritance in dose or concentration-mortality studies is discussed. Because the standard x2 statistic assumes that the only source of variability is the random binomial variation, this test is not applicable in many cases. Deriving an appropriate method for determining mode of inheritance should include a study of the sources of variation in the given set of experiments. Such a method is given for a study of cyhexatin and propargite resistances in Pacific spider mite, Tetranychus pacificus McGregor. The procedure includes the use of a modified x2 statistic that is appropriate for the analysis of bioassay data with extra sources of variation between replicates at the same dose.