Curcumin induces apoptosis in human gastric carcinoma AGS cells and colon carcinoma HT-29 cells through mitochondrial dysfunction and endoplasmic reticulum stress

Cleavage of BID by Caspase 8 Mediates the Mitochondrial Damage in the Fas Pathway of Apoptosis

Honglin Li, Hong Zhu, Chi-jie Xu et al. · Cell · 1998 · 4.4K citations · Full text

Life Sciences, Cell Biology, Molecular Biology +15

Gadd153 Sensitizes Cells to Endoplasmic Reticulum Stress by Down-Regulating Bcl2 and Perturbing the Cellular Redox State

Karen D. McCullough, Jennifer L. Martindale, Lars‐Oliver Klotz et al. · Molecular and Cellular Biology · 2001 · 1.9K citations · Full text

Life Sciences, Cell Biology, Molecular Biology +17

Phase I Clinical Trial of Oral Curcumin

Ricky A. Sharma, Stephanie A. Euden, Sharon L. Platton et al. · Clinical Cancer Research · 2004 · 1.2K citations · Full text

Medicine, Oncology, Pharmacology +13

Bcl-2 decreases the free Ca ²⁺ concentration within the endoplasmic reticulum

Reyhaneh Foyouzi-Youssefi, Serge Arnaudeau, Christoph Borner et al. · Proceedings of the National Academy of Sciences · 2000 · 420 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +12

β-Catenin-mediated transactivation and cell–cell adhesion pathways are important in curcumin (diferuylmethane)-induced growth arrest and apoptosis in colon cancer cells

Aruna S. Jaiswal, Benjamin P Marlow, Nirupama Gupta et al. · Oncogene · 2002 · 363 citations

Life Sciences, Cell Biology, Oncology +11