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Studies of the Metabolic Effects Induced in the Rat by a High Fat Diet - II. Disposal of Orally Administered (14C)-Glucose*
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1972
Year
NutritionHigh Fat DietOrally AdministeredExperimental NutritionObesityMetabolic SyndromeBody CompositionMetabolic Effects InducedMetabolic StateHealth SciencesAnimal PhysiologyCarbohydrate Synthetic DietLiver PhysiologyInsulin ManagementIngestionPharmacologyMetabolic ComplicationLipid Metabolism1.5-2 Gm/kg BodyPhysiologyDiabetesMetabolismMedicine
(6-14C) glucose (1.5-2 gm/kg body weight) was administered orally to fasted rats fed for five weeks from weaning a fat or a carbohydrate synthetic diet. Rats were killed by decapitation at 30, 60, 120 and 180 minutes after the load. 14C in the gut, glucose. (6-14C) glucose and insulin in the serum, glycogen and (14C) glycogen in the liver, were measured.