Concepedia

Altered Distribution of the Gangliosides GM1 and GM2 in Alzheimer’s Disease

Zarah Pernber, Kaj Blennow, Nenad Bogdanović, Jan‐Eric Månsson, Maria Blomqvist

Dementia and Geriatric Cognitive Disorders · 2012 · 54 citations · 51 references

DOI

Abstract

Our study supports the biochemical finding of ganglioside accumulation in cellular membranes of AD patients and shows a redistribution of these molecules.

References

51

Clinical diagnosis of Alzheimer's disease

Guy M. McKhann, David A. Drachman, Marshall Folstein et al. · Neurology · 1984 · 27.8K citations · Full text

Functional rafts in cell membranes

Kai Simons, Elina Ikonen · Nature · 1997 · 9.6K citations

, , +9

The Consortium to Establish a Registry for Alzheimer's Disease (CERAD)

Suzanne S. Mirra, Albert Heyman, Daniel W. McKeel et al. · Neurology · 1991 · 5K citations

Amyloid plaque core protein in Alzheimer disease and Down syndrome.

Colin L. Masters, G. Simms, Nicola A. Weinman et al. · Proceedings of the National Academy of Sciences · 1985 · 4.4K citations · Full text

, , +15

Lipid Rafts As a Membrane-Organizing Principle

Daniel Lingwood, Kai Simons · Science · 2009 · 4.3K citations