Vigabatrin has an anxiolytic effect in the elevated plus-maze test of anxiety

Validation of open : closed arm entries in an elevated plus-maze as a measure of anxiety in the rat

Sharon Pellow, Philippe Chopin, Sandra E. File et al. · Journal of Neuroscience Methods · 1985 · 5.8K citations

Social Sciences, Behavioral Sciences, Psychology +9

Validity of head-dipping as a measure of exploration in a modified hole-board

Sandra E. File, Ann G. Wardill · Psychopharmacology · 1975 · 666 citations

Social Sciences, Psychology, Experimental Design +3

Substantia Nigra: Site of Anticonvulsant Activity Mediated by γ-Aminobutyric Acid

Michael J. Iadarola, Karen Gale · Science · 1982 · 599 citations

Life Sciences, Neuroscience, Pharmacology +17

Benzodiazepine/GABA Receptors and Chloride Channels: Structural and Functional Properties.

Peter Jenner · Journal of Neurology Neurosurgery & Psychiatry · 1987 · 371 citations

Life Sciences, Neuroscience, Pharmacology +16

Temporal Lobe Epilepsy - A Syndrome Of Sensory-Limbic Hyperconnection

David M. Bear · Cortex · 1979 · 270 citations

Medicine, Neurology, Neuroscience +14