One-Pot, Pd-Catalyzed Synthesis of <i>trans</i>-Dihydrobenzofurans from <i>o</i>-Aminophenols

Abstract

An efficient and facile synthesis of trans-dihydrobenzofurans has been accomplished from o-aminophenols and phenylpropenes via a novel (one-pot) diastereoselective Pd-catalyzed oxyarylation reaction. The development and optimization of this method is described.