The Gene Expression of Ubiquitin Ligase E3α Is Upregulated in Skeletal Muscle during Sepsis in Rats—Potential Role of Glucocorticoids

Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction

Analytical Biochemistry · 1987 · 63.2K citations

Nucleic Acid Chemistry, Engineering, Natural Sciences +7

Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction

Piotr Chomczyński, Nicoletta Sacchi · Analytical Biochemistry · 1987 · 46.8K citations

Engineering, Natural Sciences, Rna Isolation +7

Metabolic acidosis stimulates muscle protein degradation by activating the adenosine triphosphate-dependent pathway involving ubiquitin and proteasomes.

William E. Mitch, Ruth Medina, S Grieber et al. · Journal of Clinical Investigation · 1994 · 403 citations · Full text

Muscle Function, Proteasome, Metabolic Remodeling +20

Risk Factors for Postoperative Pneumonia

John A. Windsor, Graham L. Hill · Annals of Surgery · 1988 · 287 citations · Full text

Sepsis is associated with increased mRNAs of the ubiquitin-proteasome proteolytic pathway in human skeletal muscle.

Greg Tiao, Scott C. Hobler, J J Wang et al. · Journal of Clinical Investigation · 1997 · 264 citations · Full text

Muscle Tissue, Immunology, Proteasome +20