The role of reactive oxygen species in morphine addiction of SH-SY5Y cells

μ-Opioid receptor desensitization by β-arrestin-2 determines morphine tolerance but not dependence

Laura Bohn, Raul R. Gainetdinov, Fang‐Tsyr Lin et al. · Nature · 2000 · 901 citations

Molecular Pharmacology, Addiction, Medicine +10

Role for G protein-coupled receptor kinase in agonist-specific regulation of μ-opioid receptor responsiveness

Jie Zhang, Stephen S. G. Ferguson, Larry S. Barak et al. · Proceedings of the National Academy of Sciences · 1998 · 508 citations · Full text

Neuropeptides, Pharmacotherapy, Agonist-specific Regulation +19

Organometal-induced increases in oxygen reactive species: The potential of 2′,7′-dichlorofluorescin diacetate as an index of neurotoxic damage

Carl LeBel, Syed F. Ali, M. McKee et al. · Toxicology and Applied Pharmacology · 1990 · 314 citations · Full text

Biochemistry, Medicine, Organometal-induced Increases +10

Opiate-dependent modulation of adenylate cyclase.

S K Sharma, Werner A. Klee, Marshall W. Nirenberg · Proceedings of the National Academy of Sciences · 1977 · 269 citations · Full text

Molecular Pharmacology, Molecular Physiology, Biochemistry +14

Adenylylcyclase Supersensitization in μ-Opioid Receptor-transfected Chinese Hamster Ovary Cells Following Chronic Opioid Treatment

Tomer Avidor‐Reiss, Michael Bayewitch, Rivka Levy et al. · Journal of Biological Chemistry · 1995 · 171 citations · Full text