Improved liquid chromatographic method for mitoxantrone quantification in mouse plasma and tissues to study the pharmacokinetics of a liposome entrapped mitoxantrone formulation

Controlled destabilization of a liposomal drug delivery system enhances mitoxantrone antitumor activity

Gitanjali Adlakha-Hutcheon, Marcel B. Bally, Clifford R. Shew et al. · Nature Biotechnology · 1999 · 121 citations

Pharmacy, Pharmaceutics, Pharmacology +14

Improved safety, pharmacokinetics and therapeutic efficacy profiles of a novel liposomal formulation of mitoxantrone.

Prafulla C. Gokhale, Jin Pei, Chuanbo Zhang et al. · PubMed · 2002 · 39 citations

Pharmacy, Pharmacokinetics, Pharmacology +16

High-performance liquid chromatographic determination of mitoxantrone in plasma utilizing non-bonded silica gel for solid-phase isolation to reduce adsorptive losses on glass during sample preparation

Kun T. Lin, Georges E. Rivard, Jean-Marie Leclerc · Journal of Chromatography A · 1989 · 25 citations

Pharmacy, Chemistry, Pharmacology +14

Evaluation of mitoxantrone-loaded albumin microspheres following intraperitoneal administration to rats

Christian P. Luftensteiner, Ilse Schwendenwein, Bettina Paul et al. · Journal of Controlled Release · 1999 · 23 citations

Pharmacy, Pharmacokinetics, Pharmacology +12

Comparative pharmacokinetic and cytotoxic analysis of three different formulations of mitoxantrone in mice

K.M. Rentsch, R.A. Schwendener, Heidi Wunderli‐Allenspach et al. · British Journal of Cancer · 1997 · 19 citations · Full text

Pharmacy, Pharmacokinetics, Pharmacology +10