Evaluation of natural products on inhibition of inducible cyclooxygenase (COX-2) and nitric oxide synthase (iNOS) in cultured mouse macrophage cells

Suppression of Intestinal Polyposis in ApcΔ716 Knockout Mice by Inhibition of Cyclooxygenase 2 (COX-2)

Masanobu Oshima, Joseph Dinchuk, Stacia Kargman et al. · Cell · 1996 · 2.4K citations · Full text

Life Sciences, Cell Biology, Molecular Genetics +16

TIS10, a phorbol ester tumor promoter-inducible mRNA from Swiss 3T3 cells, encodes a novel prostaglandin synthase/cyclooxygenase homologue

Dean A. Kujubu, Bradley S. Fletcher, Brian Varnum et al. · Journal of Biological Chemistry · 1991 · 1.8K citations · Full text

Life Sciences, Biochemistry, Molecular Biology +14

Selective inhibition of inducible cyclooxygenase 2 in vivo is antiinflammatory and nonulcerogenic.

Jaime L. Masferrer, Ben S. Zweifel, Pamela T. Manning et al. · Proceedings of the National Academy of Sciences · 1994 · 1.3K citations

Veterinary Medicine, Immunology, Pharmacology +17

Enzyme immunoassays of eicosanoids using acetylcholine esterase as label: an alternative to radioimmunoassay

P. Pradelles, Jacques Grassi, Jacques Maclouf · Analytical Chemistry · 1985 · 704 citations

Life Sciences, Pharmacology, Analytical Toxicology +10

Nitric oxide synthase activity in human breast cancer

LL Thomsen, DW Miles, Lisa Happerfield et al. · British Journal of Cancer · 1995 · 631 citations

Medicine, Biochemistry, Oncology +7