Disarming <i>Burkholderia pseudomallei</i> : Structural and Functional Characterization of a Disulfide Oxidoreductase (DsbA) Required for Virulence <i>In Vivo</i>

Abstract

These data establish a critical role for BpsDsbA in B. pseudomallei infection, which in combination with our structural characterization of BpsDsbA will facilitate the future development of rationally designed inhibitors against this drug-resistant organism.