Pd(II)-Catalyzed Enantioselective C−H Olefination of Diphenylacetic Acids

Abstract

Pd(II)-catalyzed enantioselective C-H olefination of diphenylacetic acid substrates has been achieved through the use of monoprotected chiral amino acid ligands. The absolute configuration of the resulting olefinated products is consistent with that of a proposed C-H insertion intermediate.