Steroid hormone metabolites potentiate GABA receptor-mediated chloride ion flux with nanomolar potency

Steroid Hormone Metabolites Are Barbiturate-Like Modulators of the GABA Receptor

Maria Dorota Majewska, Neil L. Harrison, Rochelle D. Schwartz et al. · Science · 1986 · 2.2K citations

Medicine, Neuroscience, Pharmacology +17

Anxiolytic activity of an endogenous adrenal steroid

Jacqueline N. Crawley, John R. Glowa, Maria Dorota Majewska et al. · Brain Research · 1986 · 320 citations

Life Sciences, Endocrinology, Pharmacology +14

GABA-dependent modulation of the Cl− ionophore by steroids in rat brain

Kelvin W. Gee, Wen-Chung Chang, Roberta Dı́az Brinton et al. · European Journal of Pharmacology · 1987 · 194 citations

Life Sciences, Neuroscience, Pharmacology +16

gamma-Aminobutyric acid (GABA)- and barbiturate-mediated 36Cl- uptake in rat brain synaptoneurosomes: evidence for rapid desensitization of the GABA receptor-coupled chloride ion channel.

Rochelle D. Schwartz, Peter D. Suzdak, Soumen Paul · Molecular Pharmacology · 1986 · 156 citations

Life Sciences, Neuroscience, Pharmacology +17

Benzodiazepine Enhancement of γ‐Aminobutyric Acid‐Mediated Chloride Ion Flux in Rat Brain Synaptoneurosomes

A. Leslie Morrow, Steven M. Paul · Journal of Neurochemistry · 1988 · 86 citations

Life Sciences, Neuroscience, Pharmacology +14