Cyclooxygenase-2 is Highly Expressed in Carcinoma in Situ and T1 Transitional Cell Carcinoma of the Bladder

Abstract

COX-2 is expressed in a high percent of patients with carcinoma in situ and stage T1 transitional cell carcinoma, supporting the rationale for chemoprevention studies with selective COX-2. We could not substantiate a role for COX-2 immunohistochemistry for the staging and prognosis of carcinoma in situ and/or stage T1 transitional cell carcinoma.