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Antiplasmodial constituents of <i>Cajanus cajan</i>
134
Citations
16
References
2004
Year
BiosynthesisBiochemistryMedicineHerbal MedicineMalariaBetulinic AcidPhytopharmacologyBioactivity-guided FractionationPhytochemicalMicrobiologyPhytochemistryPharmacologyCajanus CajanAntiplasmodial Constituents
Bioactivity-guided fractionation of extracts of roots and leaves of Cajanus cajan afforded 8 compounds: betulinic acid, biochanin A, cajanol, genistein and 2'-hydroxygenistein, longistylin A and C, and pinostrobin. The two stilbenes, longistylin A and C, and betulinic acid showed a moderately high in vitro activity against the chloroquine-sensitive Plasmodium falciparum strain 3D7.
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