Concepedia

Publication | Open Access

Hemodynamic effects of urotensin II and its specific receptor antagonist palosuran in cirrhotic rats†

DOIFull Paper Access

87

Citations

36

References

2008

Year

Jonel Trebicka, Ludger Leifeld, Martin Hennenberg, Erwin Biecker, Andreas Eckhardt, Nicolas Fischer, Andrea Schulze Pröbsting, Christoph R. Clemens, Frank Lammert, Tilman Sauerbruch,
Hepatology

Abstract

In BDL rats, U-II is a mediator of splanchnic vasodilation, portal hypertension and renal sodium retention. The U-II-receptor antagonist palosuran might represent a new therapeutic option in liver cirrhosis with portal hypertension.

References

YearCitations

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