Concepedia

Publication | Open Access

Activation of Nuclear Receptor Nur77 by 6-Mercaptopurine Protects Against Neointima Formation

DOIFull Paper Access

73

Citations

22

References

2007

Year

Nuno Pires, Thijs W.H. Pols, Margreet R. de Vries, Claudia M. van Tiel, Peter I. Bonta, Mariska Vos, E. Karin Arkenbout, Hans Pannekoek, J. Wouter Jukema, Paul H.A. Quax,
Circulation

Abstract

Enhancement of the activity of Nur77 by 6-MP protects against excessive SMC proliferation and SMC-rich neointima formation. We propose that activation of the nuclear receptor Nur77 is a rational approach to treating in-stent restenosis.

References

YearCitations

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