Organoiodine(<scp>iii</scp>) mediated intramolecular oxidative cyclization of 1-(3-arylisoquinolin-1-yl)-2-(arylmethylene)hydrazines to 5-aryl-3-(aryl)-[1,2,4]triazolo[3,4-a] isoquinolines

Abstract

Intramolecular C–N bond formation is achieved through oxidative cyclization of 1-(3-arylisoquinolin-1-yl)-2-(arylmethylene)hydrazines,<bold>3</bold>, in the presence of hypervalent iodine oxidant and dichloromethane at ambient temperature.