Internal Medicine · 1997 · 15 citations · 6 references
MedicineCardiologyInternal MedicineCardiac Nuclear MedicineClinical CardiologyInterventional CardiologyAcute Coronary SyndromesCardiac CatheterizationCardiovascular PathophysiologyCoronary Artery DiseaseIntracoronary ImagingIschemic Heart DiseaseAcute Myocardial Infarction DiagnosisCardiac Catheterization FindingsCardiac Sympathetic Innervation ImagingCardiovascular Autonomic NeuropathySympathetic NeuropathyVasospasm DetectionVasospastic Angina
We treated a 23-year-old male with neurofibromatosis with acute myocardial infarction. Cardiac catheterization revealed severe organic stenosis in the left anterior descending artery, an ectasic left circumflex artery and a small right coronary artery. Percutaneous transluminal coronary angioplasty (PTCA) was performed on the stenosis. In follow-up catheterizations, intracoronary administration of ergometrine induced vasospasm of the left coronary artery including at the PTCA site. An I 123 metaiodobenzylguanidine (MIBG) scintigram showed defects in the septum, inferior wall and apex. These findings suggest abnormality of the cardiac sympathetic nerve in neurofibromatosis.
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