Structure of rat behavior in hole-board: II) multivariate analysis of modifications induced by diazepam

Validation of open : closed arm entries in an elevated plus-maze as a measure of anxiety in the rat

Sharon Pellow, Philippe Chopin, Sandra E. File et al. · Journal of Neuroscience Methods · 1985 · 5.8K citations

Social Sciences, Behavioral Sciences, Psychology +9

The Economic Burden of Anxiety Disorders in the 1990s

Paul E. Greenberg, Tamar Sisitsky, Ronald C. Kessler et al. · The Journal of Clinical Psychiatry · 1999 · 1.2K citations

Education, Pharmacoeconomics, Psychiatry +17

Validity of head-dipping as a measure of exploration in a modified hole-board

Sandra E. File, Ann G. Wardill · Psychopharmacology · 1975 · 666 citations

Social Sciences, Psychology, Experimental Design +3

Changes in head-dipping behavior in the hole-board test reflect the anxiogenic and/or anxiolytic state in mice

Hiroshi Takeda, Minoru Tsuji, Teruhiko Matsumiya · European Journal of Pharmacology · 1998 · 457 citations

Medicine, Neurobiology, Neuroscience +6

Generalized anxiety disorder: nature and course.

Hans‐Ulrich Wïttchen, Jürgen Hoyer · PubMed · 2001 · 345 citations

Education, Psychiatry, Psychology +17