Monte Carlo investigation of collimator scatter of proton-therapy beams produced using the passive scattering method

TLDR

Edge‑scattered protons from the field‑limiting aperture degrade dose distributions in proton therapy and are difficult to model analytically. This study aimed to quantify the dosimetric impact of edge‑scattered protons across a representative set of clinical treatment beams. Monte Carlo simulations of proton beams from a contemporary facility were performed, varying range (6.4–28.5 cm), SOBP width (2–16 cm), field size (3×3 to 15×15 cm²), and air gap (8–48 cm). The simulations showed that edge‑scattered dose increased with range (6–20 % at the Bragg peak center), decreased with field size (2–20 %), rose modestly with air gap (2–6 %) and weakly with SOBP width (<4 %), being greatest at shallow depths and indicating that accurate monitor‑unit dose calculations must account for this effect, especially for small fields and deep targets.

Abstract

As a proton-therapy beam passes through the field-limiting aperture, some of the protons are scattered off the edges of the collimator. The edge-scattered protons can degrade the dose distribution in a patient or phantom, and these effects are difficult to model with analytical methods such as those available in treatment planning systems. The objective of this work was to quantify the dosimetric impact of edge-scattered protons for a representative variety of clinical treatment beams. The dosimetric impact was assessed using Monte Carlo simulations of proton beams from a contemporary treatment facility. The properties of the proton beams were varied, including the penetration range (6.4-28.5 cm), width of the spread-out Bragg peak (SOBP; 2-16 cm), field size (3 x 3 cm(2) to 15 x 15 cm(2)) and air gap, i.e. the distance between the collimator and the phantom (8-48 cm). The simulations revealed that the dosimetric impact of edge-scattered protons increased strongly with increasing range (dose increased by 6-20% with respect to the dose at the center of the spread-out Bragg peak), decreased strongly with increasing field size (dose changed by 2-20%), increased moderately with increasing air gap (dose increased by 2-6%) and increased weakly with increasing SOBP width (dose change <4%). In all cases examined, the effects were largest at shallow depths. We concluded that the dose deposited by edge-scattered protons can distort the dose proximal to the target with varying contributions due to the proton range, treatment field size, collimator position and thickness, and width of the SOBP. Our findings also suggest that accurate predictions of dose per monitor-unit calculations may require taking into account the dose from protons scattered from the edge of the patient-specific collimator, particularly for fields of small lateral size and deep depths.