Effects of extracellular calcium concentration on neurite outgrowth in PC12 cells by staurosporine

Staurosporine, a potent inhibitor of phospholipidCa++dependent protein kinase

Tatsuya Tamaoki, Hisayo Nomoto, ISAMI TAKAHASHI et al. · Biochemical and Biophysical Research Communications · 1986 · 2.5K citations

Phospholipidca++dependent Protein Kinase, Signal Transduction, Biochemistry +8

Calcium - a life and death signal

Michael J. Berridge, Martin D. Bootman, Peter Lipp · Nature · 1998 · 2K citations

Molecular Physiology, Neurophysiology, Longevity +8

Distinct aspects of neuronal differentiation encoded by frequency of spontaneous Ca2+ transients

Xiaonan Gu, Nicholas C. Spitzer · Nature · 1995 · 532 citations

Neurodynamics, Neurophysiology, Physiology +11

A derivative of staurosporine (CGP 41 251) shows selectivity for protein kinase C inhibition and <i>In vitro</i> anti‐proliferative as well as <i>In vivo</i> anti‐tumor activity

Thomas Meyer, Urs Regenass, Doriano Fabbro et al. · International Journal of Cancer · 1989 · 408 citations

Calcium and reactive oxygen species mediate staurosporine-induced mitochondrial dysfunction and apoptosis in PC12 cells

Inna I. Kruman, Qing Guo, Mark P. Mattson · Journal of Neuroscience Research · 1998 · 380 citations