Publication | Open Access
Cloning and chromosomal localization of a human endothelin ETA receptor
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Citations
11
References
1991
Year
GeneticsEmbryologySegregation PatternCell SignalingPlacental DevelopmentMolecular PhysiologyHormonal ReceptorReceptor (Biochemistry)Vascular BiologyPlacenta Cdna LibraryEndocrinologyHuman Endothelin ReceptorCell BiologySignal TransductionDevelopmental BiologyPhysiologySystems BiologyMedicineChromosomal Localization
A cDNA clone encoding a human endothelin receptor was isolated from a placenta cDNA library. The deduced amino acid sequence of the clone is 94% identical to the bovine endothelin ETA receptor and represents the human homologue. The human endothelin ETA receptor gene was localized to chromosome 4 by analysis of its segregation pattern in rodent-human hybrids.
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