Distribution and quantitation of the anti-trypanosomal diamidine 2,5-bis(4-amidinophenyl)furan (DB75) and its N-methoxy prodrug DB289 in murine brain tissue

Structure-In Vitro Activity Relationships of Pentamidine Analogues and Dication-Substituted Bis-Benzimidazoles as New Antifungal Agents

Maurizio Del Poeta, Wiley A. Schell, Christine C. Dykstra et al. · Antimicrobial Agents and Chemotherapy · 1998 · 223 citations · Full text

Life Sciences, Microbiology, Pharmacology +16

Synthesis and antiprotozoal activity of 2,5-bis(4-guanylphenyl)furans

Bijan Das, David W. Boykin · Journal of Medicinal Chemistry · 1977 · 142 citations

Natural Sciences, Chemistry, Pharmacology +13

Structure-activity relationships of analogs of pentamidine against Plasmodium falciparum and Leishmania mexicana amazonensis

Constance A. Bell, James Edwin Hall, Dennis E. Kyle et al. · Antimicrobial Agents and Chemotherapy · 1990 · 100 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +16

Anti-pneumocystis activity of bis-amidoximes and bis-o-alkylamidoximes prodrugs

David W. Boykin, Arvind Kumar, James Edwin Hall et al. · Bioorganic & Medicinal Chemistry Letters · 1996 · 99 citations

Pharmacy, Medicinal Chemistry, Pharmacology +11

Structure-activity studies of dicationically substituted bis-benzimidazoles against Giardia lamblia: correlation of antigiardial activity with DNA binding affinity and giardial topoisomerase II inhibition

Constance A. Bell, Christine C. Dykstra, Noreen Naiman et al. · Antimicrobial Agents and Chemotherapy · 1993 · 94 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +13